Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce

This Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce is the ultimate comfort food for pasta lovers. Tender spaghetti noodles are coated in a luscious, cheesy cream sauce with bold Cajun seasoning, then topped with juicy chicken breast for a satisfying, flavorful dinner. It’s the perfect mix of creamy, spicy, and cheesy that makes every bite irresistible.

Why You’ll Love This Recipe

Creamy & Cheesy – A rich mozzarella-garlic cream sauce that clings to every strand of pasta.
Bold Cajun Flavor – Just the right amount of heat balanced with creamy goodness.
Hearty & Filling – Protein-packed chicken with spaghetti makes it a full meal.
One-Pot Style – Easy prep, simple ingredients, and a restaurant-quality dish at home.

Ingredients

For the Chicken:

• 2 large chicken breasts (or thighs), cut into strips
• 1 ½ tbsp Cajun seasoning
• 1 tbsp olive oil
• Salt & black pepper, to taste

For the Sauce:

• 3 tbsp butter
• 4 garlic cloves, minced
• 2 tbsp all-purpose flour
• 2 cups chicken broth
• 1 ½ cups heavy cream
• 1 ½ cups shredded mozzarella cheese
• ½ cup grated Parmesan cheese
• 1 tsp Cajun seasoning (adjust to taste)
• ½ tsp red pepper flakes (optional, for extra heat)
• Salt & pepper, to taste

For the Pasta:

• 12 oz spaghetti
• 2 tbsp fresh parsley, chopped (for garnish)

Instructions

1. Cook the Pasta
   Bring a large pot of salted water to a boil. Cook spaghetti until al dente according to package directions. Drain and set aside.
2. Cook the Chicken
   Season chicken strips with Cajun seasoning, salt, and pepper. Heat olive oil in a skillet over medium-high heat. Cook chicken for 5–6 minutes until golden brown and cooked through. Remove from skillet and set aside.
3. Make the Garlic Mozzarella Sauce
   In the same skillet, melt butter. Add garlic and sauté until fragrant (about 1 minute). Stir in flour and cook for another minute. Gradually whisk in chicken broth and heavy cream until smooth.
4. Add Cheese & Seasoning
   Reduce heat to low and stir in mozzarella and Parmesan until melted and creamy. Season with Cajun seasoning, red pepper flakes, salt, and pepper to taste.
5. Combine
   Toss cooked spaghetti into the sauce until well coated. Return chicken strips to the pan, stirring gently so everything is evenly coated in the creamy sauce.
6. Serve
   Garnish with fresh parsley and extra Parmesan if desired. Serve hot.

Nutritional Information

Calories: ~620
Protein: 38g
Fat: 28g
Carbohydrates: 50g
Fiber: 2g
Sugar: 3g

Tips for Success

• Adjust Heat – Add more or less Cajun seasoning depending on spice preference.
• Extra Garlic Kick – If you’re a garlic lover, add roasted garlic for deeper flavor.
• Cheese Swap – Mozzarella gives creaminess, but you can add cheddar for a sharper bite.

Why This Recipe Works

The Cajun spices balance perfectly with the creamy mozzarella-garlic sauce, creating a pasta that’s rich yet bold. The chicken adds heartiness, while the spaghetti carries the sauce beautifully for a dish that feels indulgent but comforting.

This Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce is the perfect weeknight dinner when you crave something satisfying and full of flavor. Creamy, cheesy, and a little spicy, it’s a recipe the whole family will ask for again and again.